Signal integration in interneuron dendrites
We use patch-clamp recordings, voltage- and calcium-sensitive dye imaging techniques as well as anatomical methods to investigate how interneuron dendrites integrate and propagate voltage signals.
Synaptic plasticity on interneurons
We study how excitatory synapses on GABAergic interneurons undergo plastic changes such as long term potentiation.
GABAergic synapse function in neuronal circuits
Employing a variety of electrophyiological, imaging and computational methods we examine the functional properties of GABAergic synapses and how they contribute to microcircuit function.
We investigate how interneurons are functionally integrated in developing cortical circuits.
Interneuron pathologies in psychiatric disease
Using a panel of in vivo, in vitro and in silico techniques we study how interneuron dysfunction relates to psychiatric diseases such as depression.
Hippocampal network activity during virtual navigation
Using 2-photon imaging of genetically encoded calcium indicators in awake mice we investigate neural activity patterns which drive spatial learning in a virtual environment.