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- Top-down afferents to neocortical layer 1
- Bottom-up and top-down information streams are segregated.
- Top-down information is relayed by thalamic synapses (orange), which are controlled by ‘gatekeeper’ neurons (blue).
- Encoding of the learned relevance of sensory information at the population level in neocortex.
- Rapid neuromodulation of layer 1 interneurons in mouse and human neocortex.
- Two distinct types of inhibition control dendrites in layer 1.